Apigenin is the main active ingredient of Chamomil Extract. Chamomile is rich in flavonoid active ingredients, which have antioxidant, anti-angiogenic, anti-inflammatory, anti-allergic and anti-viral effects. The active ingredients of chamomile can be applied to high-end anti-sensitive skin care products through issofree technology. It has a good soothing effect on itchy skin, it gently replenishes water and soothes the skin. Apigenin is a potent P450 inhibitor for CYP2C9 with Ki of 2 μM.