2-Ethylhexyl Salicylate
Octisalate, Octyl Salicylate, Ethylhexyl salicylate
水杨酸盐, 水杨酸-2-乙基己基酯, 水杨酸乙基己酯
分子量:250.33 Cas No:118-60-5
紫外线吸收剂,为有机化合物,自浓缩之水杨酸与2-ethylhexanol制成,为无色之液体,带有些微的植物性气味,能抵挡 UVB 280-320,为防晒成份。

卫生署规定浓度限量为 5%[1]
[1] 行政院卫生署,『化粧品含有医療或毒剧药品基准(含药化粧品基准)』,2006/09/05。
a
2010-06-06

Octisalate是一种较弱的紫外线UVB防晒剂,比较安全,但会提高其他成分的皮肤吸收度。

j
2011-03-26

对孕妇及BB有影响吗?听说水样酸对BB有危害

c
2017-05-15

This is fragrance not sunscreen

2017-06-16

This ingredient can be used as UVB absorber. It also has a floral odor that might be used as a fragrance I gusess?

c
2018-04-09

Octisalate

Ethylhexyl salicylate, or octyl salicylate (Octisalate), is an organic compound used as an ingredient in sunscreens and cosmetics to absorb UVB (ultraviolet) rays from the sun. It is an ester formed by the condensation of a salicylic acid with 2-ethylhexanol. C15H22O3. https://pubchem.ncbi.nlm.nih.gov/compound/2-ethylhexyl_salicylate

A colorless to light yellowish oily liquid that works as a UVB (280-320nm) sunscreen filter with a peak absorbance at 306 nm. It's not a strong filter in itself, it's always used in combination with other sunscreen agents to further enhance the SPF and to solubilize other solid UV filters.

It has a good safety profile and is allowed to be used at a max concentration of 5% both in the US and in Europe (10% is allowed in Japan).

https://incidecoder.com/ingredients/ethylhexyl-salicylate

a
2023-04-23

Octisalate, an organic UV filter, readily absorbs through the skin at levels 10 times more than 0.5 nanograms per milliter, the FDA’s cutoff for systemic exposure. This cutoff is the maximum concentration that may be found in blood before there are potential safety concerns. The FDA has requested additional safety testing when a sunscreen is absorbed above this level (Walters 1997, Matta 2020).

The FDA 2019 proposed update suggests there is insufficient data to determine whether octisalate can be classified as safe and effective to use in sunscreens (FDA 2019). A case report showed that the chemical has been linked to allergic contact dermatitis (Singh 2007). Analysis of high throughput screening assays by the Environmental Protection Agency suggests octisalate may have endocrine effects, weakly binding to the estrogen receptor.

https://www.ewg.org/sunscreen/report/the-trouble-with-sunscreen-chemicals/

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